PEX5
Gene Ontology Biological Process
- negative regulation of protein homotetramerization [IDA]
- protein import into peroxisome matrix [IGI, IMP, NAS]
- protein import into peroxisome matrix, docking [IDA]
- protein import into peroxisome matrix, translocation [IDA]
- protein import into peroxisome membrane [IMP]
- protein targeting to peroxisome [IDA, IMP]
- protein tetramerization [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
HSD17B4
Gene Ontology Biological Process
- alpha-linolenic acid metabolic process [TAS]
- androgen metabolic process [IDA]
- bile acid biosynthetic process [TAS]
- bile acid metabolic process [TAS]
- cellular lipid metabolic process [TAS]
- estrogen metabolic process [IDA]
- fatty acid beta-oxidation [IDA]
- fatty acid beta-oxidation using acyl-CoA oxidase [TAS]
- medium-chain fatty-acyl-CoA metabolic process [IDA]
- metabolic process [IDA]
- osteoblast differentiation [IDA]
- oxidation-reduction process [IDA, IMP]
- small molecule metabolic process [TAS]
- unsaturated fatty acid metabolic process [TAS]
- very long-chain fatty-acyl-CoA metabolic process [IDA]
Gene Ontology Molecular Function- 17-beta-hydroxysteroid dehydrogenase (NAD+) activity [IDA]
- 3-hydroxyacyl-CoA dehydrogenase activity [IDA, IMP, TAS]
- 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [TAS]
- long-chain-enoyl-CoA hydratase activity [IDA, TAS]
- protein homodimerization activity [IDA]
- receptor binding [IPI]
- 17-beta-hydroxysteroid dehydrogenase (NAD+) activity [IDA]
- 3-hydroxyacyl-CoA dehydrogenase activity [IDA, IMP, TAS]
- 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [TAS]
- long-chain-enoyl-CoA hydratase activity [IDA, TAS]
- protein homodimerization activity [IDA]
- receptor binding [IPI]
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification of Peroxisomal Protein Complexes with PTS Receptors, Pex5 and Pex7, in Mammalian Cells.
Pex5 and Pex7 are cytosolic receptors for peroxisome targeting signal type-1 (PTS1) and type-2 (PTS2), respectively, and play a pivotal role in import of peroxisomal matrix proteins. Recent advance in mass spectrometry analysis has facilitated comprehensive analysis of protein-protein interaction network by a combination with immunoprecipitation or biochemical purification. In this chapter, we introduce several findings obtained by these methods ... [more]
Throughput
- High Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
PEX5 HSD17B4 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | 828759 | |
PEX5 HSD17B4 | Protein-peptide Protein-peptide An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments. | High | - | BioGRID | - |
Curated By
- BioGRID