BAIT

KIN

BTCD, KIN17, Rts2
Kin17 DNA and RNA binding protein
GO Process (3)
GO Function (3)
GO Component (3)
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Methylation of the DNA/RNA-binding protein Kin17 by METTL22 affects its association with chromatin.

Cloutier P, Lavallee-Adam M, Faubert D, Blanchette M, Coulombe B

Kin17 is a protein that was discovered through its immunoreactivity towards an antibody directed against prokaryotic RecA. Further study of Kin17 revealed a function in DNA replication and repair, as well as in pre-mRNA processing. Recently, it was found that Kin17 is methylated on lysine 135 by the newly discovered methyltransferase METTL22. To better understand the function of Kin17 and ... [more]

J Proteomics Apr. 04, 2014; 100();115-24 [Pubmed: 24140279]

Throughput

  • High Throughput

Curated By

  • BioGRID