BAIT
SSBP2
HSPC116, SOSS-B2
single-stranded DNA binding protein 2
GO Process (1)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
MCCC1
MCC-B, MCCA
methylcrotonoyl-CoA carboxylase 1 (alpha)
GO Process (7)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Integrator3, a partner of single-stranded DNA-binding protein 1, participates in the DNA damage response.
Single-stranded DNA-binding protein 1 (SSB1) plays an important role in the DNA damage response and maintenance of genomic stability. Here, by using protein affinity purification, we have identified Integrator3 (INT3) as a novel partner of SSB1. INT3 forms a complex with SSB1 by constitutively interacting with SSB1 regardless of DNA damage. However, following DNA damage, along with SSB1, INT3 relocates ... [more]
J. Biol. Chem. Oct. 30, 2009; 284(44);30408-15 [Pubmed: 19759019]
Throughput
- High Throughput
Curated By
- BioGRID