ATP6V0A4
Gene Ontology Biological Process
- ATP synthesis coupled proton transport [IBA]
- cellular iron ion homeostasis [TAS]
- excretion [IMP]
- insulin receptor signaling pathway [TAS]
- interaction with host [TAS]
- ossification [IMP]
- phagosome maturation [TAS]
- proton transport [IMP]
- regulation of pH [IMP]
- sensory perception of sound [IMP]
- transferrin transport [TAS]
- transmembrane transport [TAS]
- vacuolar acidification [IBA]
- vacuolar proton-transporting V-type ATPase complex assembly [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
PFKM
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
The a-subunit of the V-type H+-ATPase interacts with phosphofructokinase-1 in humans.
V-type or H+-ATPases are a family of ATP-dependent proton pumps that move protons across the plasma membrane at specialized sites such as kidney epithelial cells and osteoclasts as well as acidifying intracellular compartments. The 100-kDa polytopic a-subunit of this group of ATPases is suggested to play an important role in coupling the two functions of the pump, ATP hydrolysis and ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ATP6V0A4 PFKM | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID