DRD5
Gene Ontology Biological Process
- activation of adenylate cyclase activity [TAS]
- adenylate cyclase-activating G-protein coupled receptor signaling pathway [IDA]
- adenylate cyclase-activating dopamine receptor signaling pathway [IDA]
- cellular calcium ion homeostasis [TAS]
- cellular response to catecholamine stimulus [IDA]
- negative regulation of NAD(P)H oxidase activity [IDA]
- phospholipase C-activating dopamine receptor signaling pathway [TAS]
- positive regulation of adenylate cyclase activity [IDA, NAS]
- reactive oxygen species metabolic process [IDA]
- synaptic transmission [NAS]
- synaptic transmission, dopaminergic [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
GNA13
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Galpha12- and Galpha13-protein subunit linkage of D5 dopamine receptors in the nephron.
The roles of the G-protein alpha-subunits, Gs, Gi, and Gq/11, in the signal transduction of the D1-like dopamine receptors, D1 and D5, have been deciphered. Galpha12 and Galpha13, members of the 4th family of G protein subunits, are not linked with D1 receptors, and their linkage to D5 receptors is not known. Therefore, we studied the expression of Galpha12 and ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID