BAIT

KCTD15

potassium channel tetramerization domain containing 15
UPS Project
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY

CCT5

CCT-epsilon, CCTE, HEL-S-69, TCP-1-epsilon
chaperonin containing TCP1, subunit 5 (epsilon)
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

The essential player in adipogenesis GRP78 is a novel KCTD15 interactor.

Smaldone G, Pirone L, Capolupo A, Vitagliano L, Monti MC, Di Gaetano S, Pedone E

KCTD15 is a member of the K+ Channel Tetramerization Domain family, implicated in crucial physio-pathological processes. Recent evidences suggest that KCTD15 is an obesity-linked protein in humans and its Drosophila homologue is involved in food uptake. KCTD15 molecular mechanism in these processes is still unknown. To fill this gap, KCTD15 was biophysically characterized showing a folded, pentameric region endowed with ... [more]

Int. J. Biol. Macromol. Aug. 01, 2018; 115();469-475 [Pubmed: 29665387]

Throughput

  • High Throughput

Curated By

  • BioGRID