BAIT
KCTD15
potassium channel tetramerization domain containing 15
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
GSTM2
GST4, GSTM, GSTM2-2, GTHMUS
glutathione S-transferase mu 2 (muscle)
GO Process (14)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
- cellular detoxification of nitrogen compound [IDA]
- cellular response to caffeine [IDA]
- glutathione derivative biosynthetic process [TAS]
- glutathione metabolic process [IDA]
- negative regulation of ryanodine-sensitive calcium-release channel activity [IDA]
- nitrobenzene metabolic process [IDA]
- positive regulation of ryanodine-sensitive calcium-release channel activity [IDA]
- regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [IC]
- regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [IDA]
- regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [IC]
- relaxation of cardiac muscle [TAS]
- small molecule metabolic process [TAS]
- xenobiotic catabolic process [IDA]
- xenobiotic metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The essential player in adipogenesis GRP78 is a novel KCTD15 interactor.
KCTD15 is a member of the K+ Channel Tetramerization Domain family, implicated in crucial physio-pathological processes. Recent evidences suggest that KCTD15 is an obesity-linked protein in humans and its Drosophila homologue is involved in food uptake. KCTD15 molecular mechanism in these processes is still unknown. To fill this gap, KCTD15 was biophysically characterized showing a folded, pentameric region endowed with ... [more]
Int. J. Biol. Macromol. Aug. 01, 2018; 115();469-475 [Pubmed: 29665387]
Throughput
- High Throughput
Curated By
- BioGRID