BAIT
TPT1
HRF, TCTP, p02, p23, RP11-290D2.1
tumor protein, translationally-controlled 1
GO Process (6)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
POLR2G
RPB19, RPB7, hRPB19, hsRPB7
polymerase (RNA) II (DNA directed) polypeptide G
GO Process (15)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
- 7-methylguanosine mRNA capping [TAS]
- DNA repair [TAS]
- RNA splicing [TAS]
- gene expression [TAS]
- mRNA splicing, via spliceosome [TAS]
- nuclear-transcribed mRNA catabolic process, exonucleolytic [IBA]
- nucleotide-excision repair [TAS]
- positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [IBA]
- positive regulation of translational initiation [IBA]
- positive regulation of viral transcription [TAS]
- transcription elongation from RNA polymerase II promoter [TAS]
- transcription from RNA polymerase II promoter [IDA, TAS]
- transcription initiation from RNA polymerase II promoter [IBA, TAS]
- transcription-coupled nucleotide-excision repair [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification of translationally controlled tumor protein in promotion of DNA homologous recombination repair in cancer cells by affinity proteomics.
Translationally controlled tumor protein(TCTP) has been implicated in the regulation of apoptosis, DNA repair and drug resistance. However, the underlying molecular mechanisms are poorly defined. To better understand the molecular mechanisms underlying TCTP involved in cellular processes, we performed an affinity purification-based proteomic profiling to identify proteins interacting with TCTP in human cervical cancer HeLa cells. We found that a ... [more]
Oncogene Dec. 14, 2016; 36(50);6839-6849 [Pubmed: 28846114]
Throughput
- High Throughput
Curated By
- BioGRID