BAIT

TMEM41B

transmembrane protein 41B
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY

LRPPRC

CLONE-23970, GP130, LRP130, LSFC
leucine-rich pentatricopeptide repeat containing
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Stasimon/Tmem41b localizes to mitochondria-associated ER membranes and is essential for mouse embryonic development.

Van Alstyne M, Lotti F, Dal Mas A, Area-Gomez E, Pellizzoni L

Stasimon (also known as Tmem41b) is an evolutionarily conserved transmembrane protein first identified for its contribution to motor system dysfunction in animal models of the childhood neurodegenerative disease spinal muscular atrophy (SMA). Stasimon was shown to be required for normal neurotransmission in the motor circuit of Drosophila larvae and proper development of motor axons in zebrafish embryos as well as ... [more]

Biochem. Biophys. Res. Commun. Dec. 30, 2017; 506(3);463-470 [Pubmed: 30352685]

Throughput

  • High Throughput

Curated By

  • BioGRID