BAIT
GRIK2
EAA4, GLR6, GLUK6, GLUR6, GluK2, MRT6
glutamate receptor, ionotropic, kainate 2
GO Process (9)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- glutamate receptor signaling pathway [TAS]
- ion transmembrane transport [IBA]
- ionotropic glutamate receptor signaling pathway [IBA]
- positive regulation of synaptic transmission [IMP]
- regulation of short-term neuronal synaptic plasticity [IMP]
- regulation of synaptic transmission [IDA]
- synaptic transmission [TAS]
- synaptic transmission, glutamatergic [IBA]
- transport [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
GRIP1
GRIP
glutamate receptor interacting protein 1
GO Process (4)
GO Function (7)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP.
We identified four PDZ domain-containing proteins, syntenin, PICK1, GRIP, and PSD95, as interactors with the kainate receptor (KAR) subunits GluR5(2b,) GluR5(2c), and GluR6. Of these, we show that both GRIP and PICK1 interactions are required to maintain KAR-mediated synaptic function at mossy fiber-CA3 synapses. In addition, PKC alpha can phosphorylate ct-GluR5(2b) at residues S880 and S886, and PKC activity is ... [more]
Neuron Feb. 20, 2003; 37(4);625-38 [Pubmed: 12597860]
Throughput
- Low Throughput
Curated By
- BioGRID