BAIT

AIN1

SPAC15A10.08
alpha-actinin
GO Process (4)
GO Function (1)
GO Component (1)
Schizosaccharomyces pombe (972h)

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Molecular dissection of the actin-binding ability of the fission yeast α-actinin, Ain1, in vitro and in vivo.

Morita R, Takaine M, Numata O, Nakano K

A contractile ring (CR) is involved in cytokinesis in animal and yeast cells. Although several types of actin-bundling proteins associate with F-actin in the CR, their individual roles in the CR have not yet been elucidated in detail. Ain1 is the sole α-actinin homologue in the fission yeast Schizosaccharomyces pombe and specifically localizes to the CR with a high turnover ... [more]

J. Biochem. Aug. 01, 2017; 162(2);93-102 [Pubmed: 28338873]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
AIN1 ACT1
Reconstituted Complex
Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Low-BioGRID
-
AIN1 ACT1
Synthetic Lethality
Synthetic Lethality

A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.

Low-BioGRID
247209

Curated By

  • BioGRID