BAIT
SLC12A1
BSC1, NKCC2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
GO Process (6)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ATP1A1
RP4-655J12.1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
GO Process (14)
GO Function (4)
GO Component (10)
Gene Ontology Biological Process
- cardiac muscle contraction [TAS]
- cell communication by electrical coupling involved in cardiac conduction [TAS]
- cellular potassium ion homeostasis [IDA]
- cellular response to steroid hormone stimulus [IDA]
- cellular sodium ion homeostasis [IDA]
- ion transmembrane transport [TAS]
- membrane repolarization [IDA]
- membrane repolarization during cardiac muscle cell action potential [IC]
- potassium ion import [IDA]
- regulation of sodium ion transport [ISS]
- relaxation of cardiac muscle [TAS]
- response to glycoside [IDA]
- sodium ion export from cell [IDA]
- transmembrane transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Identification and biochemical localization of a Na-K-Cl cotransporter in the human placental cell line BeWo.
Several transport systems mediating the placental transport of Na, K and Cl have been described, but whether the trophoblast membrane also expresses a Na-K-Cl cotransporter that mediates the coupled movement of all three ions remains unclear. Here we show that BeWo cells, a human trophoblastic cell line, exhibit bumetanide-sensitive (86)Rb (a K surrogate) uptake. Entry via this route accounts for ... [more]
Biochem. Biophys. Res. Commun. Jul. 21, 2000; 274(1);43-8 [Pubmed: 10903893]
Throughput
- Low Throughput
Curated By
- BioGRID