BAIT
RBPJ
AOS3, CBF1, IGKJRB, IGKJRB1, KBF2, RBP-J, RBPJK, RBPSUH, SUH, csl
recombination signal binding protein for immunoglobulin kappa J region
GO Process (28)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
- DNA recombination [NAS]
- Notch signaling involved in heart development [IC]
- Notch signaling pathway [IMP, TAS]
- angiogenesis [ISS]
- atrioventricular canal development [ISS]
- blood vessel endothelial cell fate specification [ISS]
- blood vessel lumenization [ISS]
- cardiac left ventricle morphogenesis [ISS]
- dorsal aorta morphogenesis [ISS]
- endocardium morphogenesis [ISS]
- epithelial to mesenchymal transition [ISS]
- epithelial to mesenchymal transition involved in endocardial cushion formation [ISS]
- gene expression [TAS]
- labyrinthine layer blood vessel development [ISS]
- negative regulation of ossification [ISS]
- negative regulation of transcription from RNA polymerase II promoter [IMP, ISS]
- negative regulation of transcription, DNA-templated [IDA]
- outflow tract morphogenesis [ISS]
- positive regulation of BMP signaling pathway [ISS]
- positive regulation of ERBB signaling pathway [ISS]
- positive regulation of cardiac muscle cell proliferation [ISS]
- positive regulation of cell proliferation involved in heart morphogenesis [ISS]
- positive regulation of ephrin receptor signaling pathway [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of transcription of Notch receptor target [IDA]
- regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [ISS]
- transcription initiation from RNA polymerase II promoter [TAS]
- ventricular trabecula myocardium morphogenesis [ISS]
Gene Ontology Molecular Function- DNA binding [TAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- RNA polymerase II repressing transcription factor binding [IPI]
- protein binding [IPI]
- recombinase activity [NAS]
- sequence-specific DNA binding transcription factor activity [TAS]
- DNA binding [TAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- RNA polymerase II repressing transcription factor binding [IPI]
- protein binding [IPI]
- recombinase activity [NAS]
- sequence-specific DNA binding transcription factor activity [TAS]
Gene Ontology Cellular Component
Homo sapiens
PREY
SND1
TDRD11, p100
staphylococcal nuclease and tudor domain containing 1
GO Process (1)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A role for SKIP in EBNA2 activation of CBF1-repressed promoters.
EBNA2 is essential for Epstein-Barr virus (EBV) immortalization of B lymphocytes. EBNA2 functions as a transcriptional activator and targets responsive promoters through interaction with the cellular DNA binding protein CBF1. We have examined the mechanism whereby EBNA2 overcomes CBF1-mediated transcriptional repression. A yeast two-hybrid screen performed using CBF1 as the bait identified a protein, SKIP, which had not previously been ... [more]
J. Virol. Feb. 01, 2000; 74(4);1939-47 [Pubmed: 10644367]
Throughput
- Low Throughput
Related interactions
Curated By
- BioGRID