TLN1
Gene Ontology Biological Process
- activation of signaling protein activity involved in unfolded protein response [TAS]
- axon guidance [TAS]
- blood coagulation [TAS]
- cell-cell junction assembly [TAS]
- cellular component movement [NAS]
- cellular protein metabolic process [TAS]
- cytoskeletal anchoring at plasma membrane [NAS]
- endoplasmic reticulum unfolded protein response [TAS]
- muscle contraction [TAS]
- platelet activation [TAS]
- platelet aggregation [IMP]
- platelet degranulation [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
AZIN2
Gene Ontology Biological Process
- agmatine biosynthetic process [TAS]
- cellular nitrogen compound metabolic process [TAS]
- negative regulation of protein catabolic process [IDA, ISS]
- polyamine metabolic process [TAS]
- positive regulation of catalytic activity [ISS]
- positive regulation of polyamine transmembrane transport [ISS]
- putrescine transport [ISS]
- small molecule metabolic process [TAS]
- spermatogenesis [NAS]
- trans-Golgi network membrane organization [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
Inhibition of AZIN2-sv induces neovascularization and improves prognosis after myocardial infarction by blocking ubiquitin-dependent talin1 degradation and activating the Akt pathway.
We previously found that loss of lncRNA-AZIN2 splice variant (AZIN2-sv) increases cardiomyocyte (CM) proliferation and attenuates adverse ventricular remodelling post-myocardial infarction (MI). However, whether inhibition of AZIN2-sv can simultaneously induce angiogenesis and thus improve prognosis after MI is unclear.We used in situ hybridization and quantitative PCR to determine AZIN2-sv expression in endothelial cells. Knockdown and overexpression were performed to detect ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| AZIN2 TLN1 | Protein-RNA Protein-RNA An interaction is detected between and protein and an RNA in vitro. | High | - | BioGRID | - |
Curated By
- BioGRID