PCK1
Gene Ontology Biological Process
Gene Ontology Molecular Function
PCK2
Gene Ontology Biological Process
- fungal-type cell wall biogenesis [IMP]
- negative regulation of peptidyl-tyrosine phosphorylation [IMP]
- positive regulation of calcium-mediated signaling [IMP]
- regulation of alpha-glucan biosynthetic process [IMP]
- regulation of cell wall (1->3)-beta-D-glucan biosynthetic process [IMP]
- regulation of establishment or maintenance of cell polarity regulating cell shape [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Synthetic Rescue
A genetic interaction is inferred when mutations or deletions of one gene rescues the lethality or growth defect of a strain mutated or deleted for another gene.
Publication
Differential functional regulation of protein kinase C (PKC) orthologs in fission yeast.
The two PKC orthologs Pck1 and Pck2 in the fission yeast Schizosaccharomyces pombe operate in a redundant fashion to control essential functions, including morphogenesis and cell wall biosynthesis, as well as the activity of the cell integrity pathway and its core element, the MAPK Pmk1. We show here that, despite the strong structural similarity and functional redundancy of these two ... [more]
Throughput
- Low Throughput
Ontology Terms
- phenotype: metal resistance (APO:0000090)
Additional Notes
- Figure 5
- growth on MgCl2
- pck1-A399E
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| PCK2 PCK1 | Dosage Rescue Dosage Rescue A genetic interaction is inferred when over expression or increased dosage of one gene rescues the lethality or growth defect of a strain that is mutated or deleted for another gene. | Low | - | BioGRID | 248184 | |
| PCK2 PCK1 | Dosage Rescue Dosage Rescue A genetic interaction is inferred when over expression or increased dosage of one gene rescues the lethality or growth defect of a strain that is mutated or deleted for another gene. | Low | - | PomBase | - | |
| PCK1 PCK2 | Phenotypic Suppression Phenotypic Suppression A genetic interaction is inferred when mutation or over expression of one gene results in suppression of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 2610145 | |
| PCK1 PCK2 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | BioGRID | 247253 | |
| PCK1 PCK2 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | BioGRID | 246805 |
Curated By
- BioGRID