BAIT
ETFB
MADD, FP585
electron-transfer-flavoprotein, beta polypeptide
GO Process (3)
GO Function (0)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
PREY
ACADM
ACAD1, MCAD, MCADH, RP4-682C21.1
acyl-CoA dehydrogenase, C-4 to C-12 straight chain
GO Process (9)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- carnitine biosynthetic process [IMP]
- carnitine metabolic process, CoA-linked [IMP]
- cellular lipid metabolic process [TAS]
- fatty acid beta-oxidation [IMP, TAS]
- fatty acid beta-oxidation using acyl-CoA dehydrogenase [IDA, IMP]
- medium-chain fatty acid catabolic process [IDA]
- medium-chain fatty acid metabolic process [IDA]
- oxidation-reduction process [IDA]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-crystal Structure
Interaction directly demonstrated at the atomic level by X-ray crystallography. Also used for NMR or Electron Microscopy (EM) structures. If there is no obvious bait-hit directionality to the interaction involving 3 or more proteins, then the co-crystallized proteins should be listed as a complex.
Publication
Extensive domain motion and electron transfer in the human electron transferring flavoprotein.medium chain Acyl-CoA dehydrogenase complex.
The crystal structure of the human electron transferring flavoprotein (ETF).medium chain acyl-CoA dehydrogenase (MCAD) complex reveals a dual mode of protein-protein interaction, imparting both specificity and promiscuity in the interaction of ETF with a range of structurally distinct primary dehydrogenases. ETF partitions the functions of partner binding and electron transfer between (i) the recognition loop, which acts as a static ... [more]
J. Biol. Chem. Jul. 30, 2004; 279(31);32904-12 [Pubmed: 15159392]
Throughput
- Low Throughput
Curated By
- BioGRID