BAIT
ZBTB10
RINZF
zinc finger and BTB domain containing 10
GO Process (0)
GO Function (0)
GO Component (1)
Gene Ontology Cellular Component
Homo sapiens
PREY
FXR2
FMR1L2, FXR2P
fragile X mental retardation, autosomal homolog 2
GO Process (1)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2.
Telomeres are nucleoprotein structures at the ends of linear chromosomes and present an essential feature for genome integrity. Vertebrate telomeres usually consist of hexameric TTAGGG repeats, however, in cells that use the alternative lengthening of telomeres (ALT) mechanism, variant repeat sequences are interspersed throughout telomeres. Previously, it was shown that NR2C/F transcription factors bind to TCAGGG variant repeats and contribute ... [more]
Nucleic Acids Res. Dec. 28, 2018; 47(4);1896-1907 [Pubmed: 30629181]
Throughput
- High Throughput
Curated By
- BioGRID