PKD1
Gene Ontology Biological Process
- JAK-STAT cascade [ISS]
- anatomical structure morphogenesis [TAS]
- branching morphogenesis of an epithelial tube [IDA]
- calcium ion transmembrane transport [ISS]
- calcium-independent cell-matrix adhesion [TAS]
- cartilage development [IEP]
- cell cycle arrest [ISS]
- cell-matrix adhesion [TAS]
- cytoplasmic sequestering of transcription factor [ISS]
- detection of mechanical stimulus [IBA, ISS]
- digestive tract development [IEP]
- embryonic placenta development [ISS]
- genitalia development [IEP]
- heart development [IEP]
- homophilic cell adhesion via plasma membrane adhesion molecules [TAS]
- in utero embryonic development [ISS]
- kidney development [ISS]
- lung epithelium development [IEP]
- mesonephric duct development [IEP]
- mesonephric tubule development [IEP]
- metanephric ascending thin limb development [IEP]
- metanephric collecting duct development [IEP]
- metanephric distal tubule morphogenesis [IEP]
- metanephric proximal tubule development [IEP]
- neural tube development [IEP]
- peptidyl-serine phosphorylation [ISS]
- placenta blood vessel development [ISS]
- positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [IDA]
- positive regulation of protein binding [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- protein export from nucleus [ISS]
- regulation of proteasomal protein catabolic process [IDA]
- skin development [IEP]
- spinal cord development [IEP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
PIP5K1C
Gene Ontology Biological Process
- actin cytoskeleton organization [TAS]
- adherens junction assembly [TAS]
- axon guidance [TAS]
- clathrin-mediated endocytosis [TAS]
- neutrophil chemotaxis [TAS]
- phagocytosis [TAS]
- phosphatidylinositol biosynthetic process [TAS]
- phospholipid metabolic process [TAS]
- single organismal cell-cell adhesion [TAS]
- small molecule metabolic process [TAS]
- synaptic vesicle endocytosis [TAS]
- synaptic vesicle exocytosis [TAS]
Gene Ontology Molecular Function
Biochemical Activity (Phosphorylation)
An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation.
Publication
Protein Kinase D1 regulates focal adhesion dynamics and cell adhesion through Phosphatidylinositol-4-phosphate 5-kinase type-l ?.
Focal adhesions (FAs) are highly dynamic structures that are assembled and disassembled on a continuous basis. The balance between the two processes mediates various aspects of cell behavior, ranging from cell adhesion and spreading to directed cell migration. The turnover of FAs is regulated at multiple levels and involves a variety of signaling molecules and adaptor proteins. In the present ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID