BAIT
BMI1
AW546694, Bmi-1, Pcgf4, RP23-396N6.2
Bmi1 polycomb ring finger oncogene
GO Process (17)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
- DNA methylation [IMP]
- brain development [IMP]
- cellular process [TAS]
- embryonic skeletal system development [IGI]
- embryonic skeletal system morphogenesis [IGI]
- histone acetylation [IGI]
- histone ubiquitination [IDA]
- humoral immune response [IMP]
- in utero embryonic development [IGI]
- negative regulation of apoptotic signaling pathway [IGI]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IGI, IMP]
- positive regulation of B cell proliferation [IMP]
- positive regulation of immature T cell proliferation in thymus [IMP]
- regulation of catalytic activity [IDA]
- rostrocaudal neural tube patterning [IMP]
- skeletal system development [IMP]
- somatic stem cell division [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
HSPA4
APG-2, HEL-S-5a, HS24/P52, HSPH2, RY, hsp70, hsp70RY
heat shock 70kDa protein 4
GO Process (3)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans.
The Polycomb group (PcG) genes are required to maintain homeotic genes in a silenced state during development in drosophila and mammals and are thought to form several distinct silencing complexes that maintain homeotic gene repression during development. Mutations in the PcG genes result in developmental defects and have been implicated in human cancer. Although some PcG protein domains are conserved ... [more]
Mol. Cell. Biol. Sep. 01, 2002; 22(17);6070-8 [Pubmed: 12167701]
Throughput
- Low Throughput
Curated By
- BioGRID