BAIT
PRMT7
protein arginine methyltransferase 7
GO Process (10)
GO Function (9)
GO Component (5)
Gene Ontology Biological Process
- DNA methylation involved in gamete generation [ISS]
- histone arginine methylation [IBA, ISS]
- histone methylation [IDA]
- peptidyl-arginine methylation [IDA, IMP]
- peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [IBA]
- peptidyl-arginine methylation, to symmetrical-dimethyl arginine [IDA, IMP]
- regulation of gene expression by genetic imprinting [ISS]
- regulation of protein binding [IC]
- regulation of transcription, DNA-templated [IBA]
- spliceosomal snRNP assembly [IMP]
Gene Ontology Molecular Function- S-adenosylmethionine-dependent methyltransferase activity [IDA]
- [myelin basic protein]-arginine N-methyltransferase activity [IDA]
- histone binding [IC]
- histone methyltransferase activity (H4-R3 specific) [ISS]
- histone-arginine N-methyltransferase activity [IDA]
- protein-arginine omega-N asymmetric methyltransferase activity [IBA]
- protein-arginine omega-N monomethyltransferase activity [IDA]
- protein-arginine omega-N symmetric methyltransferase activity [IDA, IMP]
- ribonucleoprotein complex binding [IPI]
- S-adenosylmethionine-dependent methyltransferase activity [IDA]
- [myelin basic protein]-arginine N-methyltransferase activity [IDA]
- histone binding [IC]
- histone methyltransferase activity (H4-R3 specific) [ISS]
- histone-arginine N-methyltransferase activity [IDA]
- protein-arginine omega-N asymmetric methyltransferase activity [IBA]
- protein-arginine omega-N monomethyltransferase activity [IDA]
- protein-arginine omega-N symmetric methyltransferase activity [IDA, IMP]
- ribonucleoprotein complex binding [IPI]
Gene Ontology Cellular Component
Homo sapiens
PREY
RPL23
L23, rpL17
ribosomal protein L23
GO Process (14)
GO Function (3)
GO Component (7)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- cellular protein metabolic process [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [TAS]
- ribosomal protein import into nucleus [NAS]
- translation [NAS, TAS]
- translational elongation [TAS]
- translational initiation [TAS]
- translational termination [TAS]
- viral life cycle [TAS]
- viral process [TAS]
- viral transcription [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
PRMT7 methylates eukaryotic translation initiation factor 2? and regulates its role in stress granule formation.
Protein arginine methyltransferases (PRMTs) are a family of enzymes that modify proteins by methylating the guanidino nitrogen atoms of arginine residues to regulate cellular processes such as chromatin remodeling, pre-mRNA splicing, and signal transduction. PRMT7 is the single type III PRMT solely capable of arginine monomethylation. To date, other than histone proteins, there are very few identified substrates of PRMT7. ... [more]
Mol. Biol. Cell Dec. 15, 2018; 30(6);778-793 [Pubmed: 30699057]
Throughput
- High Throughput
Curated By
- BioGRID