BAIT

AGRN

CMSPPD, RP11-54O7.13-009
agrin
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Agrin has a pathological role in the progression of oral cancer.

Rivera C, Zandonadi FS, Sanchez-Romero C, Soares CD, Granato DC, Gonzalez-Arriagada WA, Paes Leme AF

The extracellular matrix modulates the hallmarks of cancer. Here we examined the role of agrin-a member of this matrix-in progression of oral squamous cell carcinoma (OSCC).We evaluated the immunohistochemical expression of agrin in OSCC and dysplasias. Benign lesions were used as control. In subsequent experiments, we investigated whether the silencing of agrin interferes with tumour expansion both in vitro as ... [more]

Br. J. Cancer Dec. 01, 2017; 118(12);1628-1638 [Pubmed: 29872149]

Throughput

  • High Throughput

Curated By

  • BioGRID