BAIT
AGRN
CMSPPD, RP11-54O7.13-009
agrin
GO Process (19)
GO Function (8)
GO Component (9)
Gene Ontology Biological Process
- G-protein coupled acetylcholine receptor signaling pathway [TAS]
- axon guidance [TAS]
- carbohydrate metabolic process [TAS]
- chondroitin sulfate metabolic process [TAS]
- clustering of voltage-gated sodium channels [TAS]
- extracellular matrix organization [TAS]
- glycosaminoglycan biosynthetic process [TAS]
- glycosaminoglycan catabolic process [TAS]
- glycosaminoglycan metabolic process [TAS]
- phototransduction, visible light [TAS]
- positive regulation of Rho GTPase activity [ISS]
- positive regulation of filopodium assembly [ISS]
- positive regulation of synaptic growth at neuromuscular junction [ISS]
- positive regulation of transcription from RNA polymerase II promoter [ISS]
- receptor clustering [IDA, IMP]
- retinoid metabolic process [TAS]
- signal transduction [TAS]
- small molecule metabolic process [TAS]
- synapse organization [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
HMGA1
HMG-R, HMGA1A, HMGIY, RP11-513I15.2
high mobility group AT-hook 1
GO Process (16)
GO Function (11)
GO Component (6)
Gene Ontology Biological Process
- DNA catabolic process, endonucleolytic [IDA]
- DNA unwinding involved in DNA replication [NAS]
- base-excision repair [IDA]
- establishment of integrated proviral latency [TAS]
- negative regulation of cell proliferation [IMP]
- negative regulation of chromatin silencing [TAS]
- negative regulation of transcription, DNA-templated [IMP]
- nucleosome disassembly [TAS]
- oncogene-induced cell senescence [IDA]
- positive regulation of cellular senescence [IMP]
- positive regulation of transcription, DNA-templated [IMP]
- protein complex assembly [TAS]
- regulation of transcription, DNA-templated [TAS]
- response to virus [IEP]
- senescence-associated heterochromatin focus assembly [IDA]
- viral process [TAS]
Gene Ontology Molecular Function- 5'-deoxyribose-5-phosphate lyase activity [IDA]
- AT DNA binding [TAS]
- DNA binding [TAS]
- DNA-(apurinic or apyrimidinic site) lyase activity [IDA]
- enzyme binding [IPI]
- ligand-dependent nuclear receptor transcription coactivator activity [IMP]
- peroxisome proliferator activated receptor binding [IDA]
- protein binding [IPI]
- retinoic acid receptor binding [IDA]
- retinoid X receptor binding [IDA]
- transcription factor binding [IDA]
- 5'-deoxyribose-5-phosphate lyase activity [IDA]
- AT DNA binding [TAS]
- DNA binding [TAS]
- DNA-(apurinic or apyrimidinic site) lyase activity [IDA]
- enzyme binding [IPI]
- ligand-dependent nuclear receptor transcription coactivator activity [IMP]
- peroxisome proliferator activated receptor binding [IDA]
- protein binding [IPI]
- retinoic acid receptor binding [IDA]
- retinoid X receptor binding [IDA]
- transcription factor binding [IDA]
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Agrin has a pathological role in the progression of oral cancer.
The extracellular matrix modulates the hallmarks of cancer. Here we examined the role of agrin-a member of this matrix-in progression of oral squamous cell carcinoma (OSCC).We evaluated the immunohistochemical expression of agrin in OSCC and dysplasias. Benign lesions were used as control. In subsequent experiments, we investigated whether the silencing of agrin interferes with tumour expansion both in vitro as ... [more]
Br. J. Cancer Dec. 01, 2017; 118(12);1628-1638 [Pubmed: 29872149]
Throughput
- High Throughput
Curated By
- BioGRID