BAIT
KCNH5
EAG2, H-EAG2, Kv10.2, hEAG2
potassium voltage-gated channel, subfamily H (eag-related), member 5
GO Process (4)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
TUBB
CDCBM6, M40, OK/SW-cl.56, TUBB1, TUBB5, DAAP-285E11.4
tubulin, beta class I
GO Process (8)
GO Function (4)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Tubulin as a binding partner of the heag2 voltage-gated potassium channel.
The aim of this work was to investigate interactions of the human ether-a-go-go channel heag2 with human brain proteins. For this, we used heag2-GST fusion proteins in pull-down assays with brain proteins and mass spectrometry, as well as coimmunoprecipitation. We identified tubulin and heat shock 70 proteins as binding to intracellular C-terminal regions of the channel. To study functional effects, ... [more]
J. Membr. Biol. Apr. 01, 2008; 222(3);115-25 [Pubmed: 18458804]
Throughput
- Low Throughput
Curated By
- BioGRID