BAIT
DYNC1LI1
DNCLI1, LIC1
dynein, cytoplasmic 1, light intermediate chain 1
GO Process (1)
GO Function (1)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
TCEB2
ELOB, SIII
transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
GO Process (8)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
- cellular response to hypoxia [TAS]
- gene expression [TAS]
- positive regulation of viral transcription [TAS]
- protein complex assembly [TAS]
- regulation of transcription from RNA polymerase II promoter in response to hypoxia [TAS]
- transcription elongation from RNA polymerase II promoter [TAS]
- transcription from RNA polymerase II promoter [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
The human cytoplasmic dynein interactome reveals novel activators of motility.
In human cells, cytoplasmic dynein-1 is essential for long-distance transport of many cargos, including organelles, RNAs, proteins, and viruses, towards microtubule minus ends. To understand how a single motor achieves cargo specificity, we identified the human dynein interactome by attaching a promiscuous biotin ligase ('BioID') to seven components of the dynein machinery, including a subunit of the essential cofactor dynactin. ... [more]
Elife Dec. 18, 2016; 6(); [Pubmed: 28718761]
Throughput
- High Throughput
Curated By
- BioGRID