BAIT
DYNLRB1
BITH, BLP, DNCL2A, DNLC2A, ROBLD1, HSPC162
dynein, light chain, roadblock-type 1
GO Process (3)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ELL
C19orf17, ELL1, MEN, PPP1R68
elongation factor RNA polymerase II
GO Process (11)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- gene expression [TAS]
- negative regulation of phosphatase activity [IDA]
- positive regulation of DNA-templated transcription, elongation [TAS]
- positive regulation of transcription elongation from RNA polymerase II promoter [IMP]
- positive regulation of transcription from RNA polymerase III promoter [IMP]
- positive regulation of viral transcription [TAS]
- snRNA transcription from RNA polymerase II promoter [IMP]
- snRNA transcription from RNA polymerase III promoter [IMP]
- transcription elongation from RNA polymerase II promoter [TAS]
- transcription from RNA polymerase II promoter [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
The human cytoplasmic dynein interactome reveals novel activators of motility.
In human cells, cytoplasmic dynein-1 is essential for long-distance transport of many cargos, including organelles, RNAs, proteins, and viruses, towards microtubule minus ends. To understand how a single motor achieves cargo specificity, we identified the human dynein interactome by attaching a promiscuous biotin ligase ('BioID') to seven components of the dynein machinery, including a subunit of the essential cofactor dynactin. ... [more]
Elife Dec. 18, 2016; 6(); [Pubmed: 28718761]
Throughput
- High Throughput
Curated By
- BioGRID