BAIT
HOOK3
HK3
hook microtubule-tethering protein 3
GO Process (10)
GO Function (3)
GO Component (8)
Gene Ontology Biological Process
- Golgi localization [IMP]
- cytoplasmic microtubule organization [IMP]
- early endosome to late endosome transport [IMP]
- endosome organization [IMP]
- endosome to lysosome transport [IMP]
- interkinetic nuclear migration [ISS]
- lysosome organization [IMP]
- microtubule anchoring at centrosome [ISS]
- negative regulation of neurogenesis [ISS]
- protein localization to centrosome [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
GFPT1
CMSTA1, GFA, GFAT, GFAT 1, GFAT1, GFAT1m, GFPT, GFPT1L, MSLG
glutamine--fructose-6-phosphate transaminase 1
GO Process (9)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
- UDP-N-acetylglucosamine biosynthetic process [TAS]
- activation of signaling protein activity involved in unfolded protein response [TAS]
- cellular protein metabolic process [TAS]
- circadian regulation of gene expression [ISS]
- dolichol-linked oligosaccharide biosynthetic process [TAS]
- endoplasmic reticulum unfolded protein response [TAS]
- energy reserve metabolic process [TAS]
- post-translational protein modification [TAS]
- protein N-linked glycosylation via asparagine [TAS]
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
The human cytoplasmic dynein interactome reveals novel activators of motility.
In human cells, cytoplasmic dynein-1 is essential for long-distance transport of many cargos, including organelles, RNAs, proteins, and viruses, towards microtubule minus ends. To understand how a single motor achieves cargo specificity, we identified the human dynein interactome by attaching a promiscuous biotin ligase ('BioID') to seven components of the dynein machinery, including a subunit of the essential cofactor dynactin. ... [more]
Elife Dec. 18, 2016; 6(); [Pubmed: 28718761]
Throughput
- High Throughput
Curated By
- BioGRID