BAIT
HOOK3
HK3
hook microtubule-tethering protein 3
GO Process (10)
GO Function (3)
GO Component (8)
Gene Ontology Biological Process
- Golgi localization [IMP]
- cytoplasmic microtubule organization [IMP]
- early endosome to late endosome transport [IMP]
- endosome organization [IMP]
- endosome to lysosome transport [IMP]
- interkinetic nuclear migration [ISS]
- lysosome organization [IMP]
- microtubule anchoring at centrosome [ISS]
- negative regulation of neurogenesis [ISS]
- protein localization to centrosome [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PATL1
Pat1b, hPat1b, OK/KNS-cl.5
protein associated with topoisomerase II homolog 1 (yeast)
GO Process (7)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- cytoplasmic mRNA processing body assembly [IDA]
- deadenylation-dependent decapping of nuclear-transcribed mRNA [IDA]
- exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
The human cytoplasmic dynein interactome reveals novel activators of motility.
In human cells, cytoplasmic dynein-1 is essential for long-distance transport of many cargos, including organelles, RNAs, proteins, and viruses, towards microtubule minus ends. To understand how a single motor achieves cargo specificity, we identified the human dynein interactome by attaching a promiscuous biotin ligase ('BioID') to seven components of the dynein machinery, including a subunit of the essential cofactor dynactin. ... [more]
Elife Dec. 18, 2016; 6(); [Pubmed: 28718761]
Throughput
- High Throughput
Curated By
- BioGRID