BAIT
BICD1
BICD, RP11-817I4.1
bicaudal D homolog 1 (Drosophila)
GO Process (12)
GO Function (7)
GO Component (10)
Gene Ontology Biological Process
- RNA processing [TAS]
- anatomical structure morphogenesis [TAS]
- intracellular mRNA localization [NAS]
- microtubule anchoring at microtubule organizing center [ISS]
- minus-end-directed organelle transport along microtubule [IMP]
- negative regulation of phospholipase C activity [ISS]
- negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway [ISS]
- positive regulation of receptor-mediated endocytosis [IMP]
- protein localization to organelle [IDA]
- regulation of proteinase activated receptor activity [ISS]
- stress granule assembly [ISS]
- viral process [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
HGS
HRS
hepatocyte growth factor-regulated tyrosine kinase substrate
GO Process (13)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- endosomal transport [NAS, TAS]
- epidermal growth factor receptor signaling pathway [TAS]
- membrane invagination [IMP]
- membrane organization [TAS]
- negative regulation of JAK-STAT cascade [IDA]
- negative regulation of cell proliferation [TAS]
- negative regulation of epidermal growth factor receptor signaling pathway [TAS]
- positive regulation of exosomal secretion [IMP]
- positive regulation of gene expression [IMP]
- protein localization to membrane [IMP]
- protein targeting to lysosome [IMP]
- regulation of protein catabolic process [TAS]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
The human cytoplasmic dynein interactome reveals novel activators of motility.
In human cells, cytoplasmic dynein-1 is essential for long-distance transport of many cargos, including organelles, RNAs, proteins, and viruses, towards microtubule minus ends. To understand how a single motor achieves cargo specificity, we identified the human dynein interactome by attaching a promiscuous biotin ligase ('BioID') to seven components of the dynein machinery, including a subunit of the essential cofactor dynactin. ... [more]
Elife Dec. 18, 2016; 6(); [Pubmed: 28718761]
Throughput
- High Throughput
Curated By
- BioGRID