BAIT
MTNR1A
MEL-1A-R, MT1
melatonin receptor 1A
GO Process (4)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CSNK2A1
Csnk2a1-rs4, RP23-452D3.3
casein kinase 2, alpha 1 polypeptide
GO Process (9)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
- mitotic spindle checkpoint [ISO]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- positive regulation of Wnt signaling pathway [ISO]
- positive regulation of cell growth [ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of protein catabolic process [ISO]
- protein autophosphorylation [IDA]
- protein phosphorylation [IDA, ISO]
- regulation of catalytic activity [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-purification
An interaction is inferred from the identification of two or more protein subunits in a purified protein complex, as obtained by classical biochemical fractionation or affinity purification and one or more additional fractionation steps.
Publication
A generic approach for the purification of signaling complexes that specifically interact with the carboxyl-terminal domain of G protein-coupled receptors.
G protein-coupled receptors (GPCRs) constitute the largest family of membrane receptors and are major drug targets. Recent progress has shown that GPCRs are part of large protein complexes that regulate their activity. We present here a generic approach for identification of these complexes that is based on the use of receptor subdomains and that overcomes the limitations of currently used ... [more]
Mol. Cell Proteomics Aug. 01, 2008; 7(8);1556-69 [Pubmed: 18448421]
Throughput
- High Throughput
Curated By
- BioGRID