MAPK8IP3
Gene Ontology Biological Process
- JNK cascade [IDA]
- activation of JUN kinase activity [IDA]
- axon guidance [IMP]
- forebrain development [IMP]
- in utero embryonic development [IMP]
- lung alveolus development [IMP]
- lung morphogenesis [IMP]
- positive regulation of JUN kinase activity [IDA]
- positive regulation of neuron differentiation [ISO]
- positive regulation of signal transduction [IPI]
- post-embryonic development [IMP]
- protein localization [IMP]
- regulation of JNK cascade [IDA]
- regulation of gene expression [IDA]
- respiratory gaseous exchange [IMP]
- vesicle-mediated transport [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
MAPK10
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Role of plasma membrane localization of the scaffold protein JSAP1 during differentiation of cerebellar granule cell precursors.
We previously reported that the scaffold protein c-Jun NH?-terminal kinase (JNK)/stress-activated protein kinase-associated protein 1 (JSAP1) functions in cerebellar granule cell precursors (GCPs) to promote their cell-cycle exit and differentiation. In this study, we used immunocytochemistry to examine the subcellular distribution of JSAP1 in proliferating cultured GCPs. We found that when stimulated with fibroblast growth factor-2 (FGF-2), a factor that ... [more]
Throughput
- Low Throughput
Additional Notes
- in presence of activated FGFR
Curated By
- BioGRID