BAIT
NOTCH1
9930111A19Rik, Mis6, N1, Tan1, lin-12, RP23-306D20.12-001
notch 1
GO Process (135)
GO Function (9)
GO Component (11)
Gene Ontology Biological Process
- Notch signaling involved in heart development [IGI, IMP, ISO]
- Notch signaling pathway [IC, IDA, IMP, ISO]
- Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [IMP]
- anagen [IMP]
- aortic valve morphogenesis [ISO]
- apoptotic process involved in embryonic digit morphogenesis [IMP]
- arterial endothelial cell differentiation [IMP]
- astrocyte differentiation [ISO]
- atrioventricular node development [IMP]
- atrioventricular valve morphogenesis [IMP]
- auditory receptor cell fate commitment [IMP]
- axonogenesis [IDA, IMP]
- branching morphogenesis of an epithelial tube [IMP]
- cardiac atrium morphogenesis [IMP]
- cardiac chamber formation [IMP]
- cardiac epithelial to mesenchymal transition [IMP]
- cardiac left ventricle morphogenesis [IMP]
- cardiac muscle cell proliferation [IMP]
- cardiac muscle tissue morphogenesis [IMP]
- cardiac right atrium morphogenesis [IMP]
- cardiac right ventricle formation [IMP]
- cardiac septum morphogenesis [IMP]
- cardiac vascular smooth muscle cell development [IMP]
- cardiac ventricle morphogenesis [IMP]
- cell differentiation [IMP]
- cell fate commitment [IMP]
- cell fate specification [IMP]
- cell migration involved in endocardial cushion formation [IMP]
- cellular response to follicle-stimulating hormone stimulus [ISO]
- cellular response to vascular endothelial growth factor stimulus [ISO]
- compartment pattern specification [IMP]
- coronary artery morphogenesis [IMP]
- coronary vein morphogenesis [IMP]
- determination of left/right symmetry [IMP]
- embryonic hindlimb morphogenesis [IMP]
- embryonic limb morphogenesis [IGI]
- endocardial cell differentiation [IMP]
- endocardial cushion morphogenesis [IMP]
- endocardium development [IMP]
- endocardium morphogenesis [IMP]
- endoderm development [IMP]
- epidermis development [IGI]
- epithelial to mesenchymal transition [IMP]
- epithelial to mesenchymal transition involved in endocardial cushion formation [IMP]
- forebrain development [IGI, IMP]
- foregut morphogenesis [IMP]
- glial cell differentiation [IMP]
- growth involved in heart morphogenesis [IMP]
- hair follicle morphogenesis [IMP]
- heart development [IMP, ISO]
- heart looping [IGI]
- heart trabecula morphogenesis [IMP]
- humoral immune response [IGI]
- in utero embryonic development [IMP]
- inflammatory response to antigenic stimulus [IGI]
- interleukin-4 secretion [IGI]
- keratinocyte differentiation [IMP]
- left/right axis specification [IGI]
- liver development [IMP]
- lung development [IMP]
- mesenchymal cell development [IMP]
- mitral valve formation [ISO]
- negative regulation of BMP signaling pathway [IMP]
- negative regulation of anoikis [ISO]
- negative regulation of calcium ion-dependent exocytosis [IMP]
- negative regulation of canonical Wnt signaling pathway [IMP]
- negative regulation of catalytic activity [IDA]
- negative regulation of cell death [IMP]
- negative regulation of cell differentiation [IMP]
- negative regulation of cell migration involved in sprouting angiogenesis [ISO]
- negative regulation of cell proliferation [ISO]
- negative regulation of cell-substrate adhesion [ISO]
- negative regulation of endothelial cell chemotaxis [ISO]
- negative regulation of glial cell proliferation [IDA]
- negative regulation of myoblast differentiation [ISO]
- negative regulation of myotube differentiation [IDA]
- negative regulation of neurogenesis [IDA]
- negative regulation of neuron differentiation [IGI, IMP, ISO]
- negative regulation of oligodendrocyte differentiation [IDA]
- negative regulation of ossification [IMP]
- negative regulation of osteoblast differentiation [IMP]
- negative regulation of photoreceptor cell differentiation [IMP]
- negative regulation of pro-B cell differentiation [IMP]
- negative regulation of stem cell differentiation [ISO]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IMP]
- negative regulation of transcription, DNA-templated [IDA, IMP]
- neural tube development [IMP]
- neuron differentiation [IMP]
- neuron fate commitment [IGI]
- osteoblast fate commitment [NAS]
- pericardium morphogenesis [IMP]
- positive regulation of BMP signaling pathway [IDA]
- positive regulation of JAK-STAT cascade [IDA]
- positive regulation of apoptotic process [IDA, IGI]
- positive regulation of astrocyte differentiation [IDA]
- positive regulation of cardiac muscle cell proliferation [IMP]
- positive regulation of cell migration [IMP]
- positive regulation of cell proliferation [IGI, ISO]
- positive regulation of endothelial cell differentiation [ISO]
- positive regulation of ephrin receptor signaling pathway [IC]
- positive regulation of epithelial cell proliferation [IGI]
- positive regulation of epithelial to mesenchymal transition [IMP, ISO]
- positive regulation of glial cell differentiation [ISO]
- positive regulation of keratinocyte differentiation [IDA, IGI]
- positive regulation of neuroblast proliferation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI, IMP, ISO]
- positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [IDA]
- positive regulation of transcription of Notch receptor target [IGI, ISO]
- positive regulation of transcription, DNA-templated [IDA]
- prostate gland epithelium morphogenesis [IMP]
- pulmonary valve morphogenesis [ISO]
- regulation of cardioblast proliferation [ISO]
- regulation of cell adhesion involved in heart morphogenesis [IC]
- regulation of cell migration [IMP]
- regulation of cell proliferation [ISO]
- regulation of epithelial cell proliferation [IMP]
- regulation of epithelial cell proliferation involved in prostate gland development [IMP]
- regulation of extracellular matrix assembly [IMP]
- regulation of gene expression [IMP]
- regulation of neurogenesis [IMP]
- regulation of somitogenesis [IMP]
- regulation of transcription from RNA polymerase II promoter [IGI]
- regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [IMP]
- response to muramyl dipeptide [IDA]
- secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [IMP]
- skeletal muscle cell differentiation [IMP]
- somatic stem cell division [IDA, IGI]
- spermatogenesis [ISO]
- sprouting angiogenesis [IMP]
- transcription from RNA polymerase II promoter [IDA]
- tube formation [ISO]
- vasculogenesis involved in coronary vascular morphogenesis [IMP]
- venous endothelial cell differentiation [IMP]
- ventricular septum morphogenesis [ISO]
- ventricular trabecula myocardium morphogenesis [IMP]
Gene Ontology Molecular Function- RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription [IDA]
- chromatin DNA binding [IDA]
- chromatin binding [IDA]
- core promoter binding [IDA]
- enzyme binding [IPI]
- enzyme inhibitor activity [IDA]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
- RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription [IDA]
- chromatin DNA binding [IDA]
- chromatin binding [IDA]
- core promoter binding [IDA]
- enzyme binding [IPI]
- enzyme inhibitor activity [IDA]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
Gene Ontology Cellular Component
Mus musculus
PREY
DAB1
AI956902, C630028C02Rik, scm, scr, scrambler, yot, RP23-356E21.1
disabled 1
GO Process (20)
GO Function (4)
GO Component (9)
Gene Ontology Biological Process
- Golgi localization [IMP]
- adult walking behavior [IMP]
- cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration [IMP]
- central nervous system development [TAS]
- cerebellum structural organization [IMP]
- cerebral cortex cell migration [IMP]
- cerebral cortex radially oriented cell migration [IGI, IMP, ISO]
- dendrite development [IGI, IMP]
- intracellular signal transduction [TAS]
- lateral motor column neuron migration [IMP]
- negative regulation of JAK-STAT cascade [IMP]
- negative regulation of astrocyte differentiation [IMP]
- negative regulation of axonogenesis [IGI, IMP]
- negative regulation of cell adhesion [IMP]
- nervous system development [NAS]
- neuron migration [IGI, IMP, ISO]
- positive regulation of neuron differentiation [IMP]
- positive regulation of protein kinase activity [IGI]
- radial glia guided migration of Purkinje cell [IGI, IMP]
- small GTPase mediated signal transduction [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-localization
Interaction inferred from two proteins that co-localize in the cell by indirect immunofluorescence only when in addition, if one gene is deleted, the other protein becomes mis-localized. Also includes co-dependent association of proteins with promoter DNA in chromatin immunoprecipitation experiments.
Publication
Reelin and Notch1 cooperate in the development of the dentate gyrus.
The development of the hippocampal dentate gyrus is a complex process in which several signaling pathways are involved and likely interact with each other. The extracellular matrix molecule Reelin is necessary both for normal development of the dentate gyrus radial glia and neuronal migration. In Reelin-deficient Reeler mice, the hippocampal radial glial scaffold fails to form, and granule cells are ... [more]
J. Neurosci. Jul. 01, 2009; 29(26);8578-85 [Pubmed: 19571148]
Throughput
- Low Throughput
Curated By
- BioGRID