A genetic interaction is inferred when mutation or over expression of one gene results in suppression of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.

Publication

RNA polymerase II CTD interactome with 3' processing and termination factors in fission yeast and its impact on phosphate homeostasis.

Sanchez AM, Shuman S, Schwer B

The carboxy-terminal domain (CTD) code encrypted within the Y1S2P3T4S5P6S7 heptad repeats of RNA polymerase II (Pol2) is deeply rooted in eukaryal biology. Key steps to deciphering the code are identifying the events in gene expression that are governed by individual "letters" and then defining a vocabulary of multiletter "words" and their meaning. Thr4 and Ser7 exert opposite effects on the ... [more]

Proc. Natl. Acad. Sci. U.S.A. Dec. 06, 2017; 115(45);E10652-E10661 [Pubmed: 30355770]

Throughput

Low Throughput

Ontology Terms

protein activity (APO:0000022)

Additional Notes

Figure 3
pho1 activity

Curated By

BioGRID

Interaction Summary

CSK1

Gene Ontology Biological Process

Gene Ontology Molecular Function

cyclin-dependent protein kinase activating kinase activity [IGI]cyclin-dependent protein serine/threonine kinase regulator activity [IMP]protein kinase activator activity [IDA]protein kinase activity [IDA]protein serine/threonine kinase activity [IDA]

Gene Ontology Cellular Component

RHN1