ATP5B
Gene Ontology Biological Process
- ATP biosynthetic process [IMP]
- ATP catabolic process [IDA]
- angiogenesis [IMP]
- cellular metabolic process [TAS]
- generation of precursor metabolites and energy [NAS]
- mitochondrial ATP synthesis coupled proton transport [IC, TAS]
- osteoblast differentiation [IDA]
- proton transport [IMP]
- regulation of intracellular pH [IMP]
- respiratory electron transport chain [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cell surface [IDA]
- extracellular vesicular exosome [IDA]
- membrane [IDA]
- mitochondrial matrix [NAS, TAS]
- mitochondrial membrane [IDA]
- mitochondrial nucleoid [IDA]
- mitochondrial proton-transporting ATP synthase complex [IDA]
- mitochondrial proton-transporting ATP synthase, catalytic core [NAS]
- mitochondrion [IDA]
- nucleus [IDA]
- plasma membrane [IDA]
PHB2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.
Mitochondrial protein (MP) assemblies undergo alterations during neurogenesis, a complex process vital in brain homeostasis and disease. Yet which MP assemblies remodel during differentiation remains unclear. Here, using mass spectrometry-based co-fractionation profiles and phosphoproteomics, we generated mitochondrial interaction maps of human pluripotent embryonal carcinoma stem cells and differentiated neuronal-like cells, which presented as two discrete cell populations by single-cell RNA ... [more]
Quantitative Score
- 1.71168957 [Confidence Score]
Throughput
- High Throughput
Additional Notes
- Protein pairs with Sigma LLS score >= 1.45 derived from Ntera2 embryonic carcinoma stem cells (ECSC)
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| PHB2 ATP5B | Proximity Label-MS Proximity Label-MS An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods. | High | 85.31 | BioGRID | 2999880 |
Curated By
- BioGRID