BAIT
INHBA
EDF, FRP
inhibin, beta A
GO Process (42)
GO Function (8)
GO Component (3)
Gene Ontology Biological Process
- G1/S transition of mitotic cell cycle [IDA]
- SMAD protein signal transduction [IBA]
- activin receptor signaling pathway [IDA]
- cell cycle arrest [IDA]
- cell development [IBA]
- cell differentiation [TAS]
- cell surface receptor signaling pathway [TAS]
- cell-cell signaling [TAS]
- defense response [TAS]
- endodermal cell differentiation [IDA]
- erythrocyte differentiation [NAS]
- extrinsic apoptotic signaling pathway [IDA]
- eyelid development in camera-type eye [ISS]
- hair follicle development [IGI]
- hematopoietic progenitor cell differentiation [IDA]
- hemoglobin biosynthetic process [IDA]
- male gonad development [IGI]
- negative regulation of B cell differentiation [TAS]
- negative regulation of cell cycle [IDA]
- negative regulation of cell growth [IDA]
- negative regulation of cell proliferation [IDA]
- negative regulation of follicle-stimulating hormone secretion [NAS]
- negative regulation of interferon-gamma biosynthetic process [TAS]
- negative regulation of macrophage differentiation [TAS]
- negative regulation of phosphorylation [TAS]
- nervous system development [NAS]
- odontogenesis [IGI]
- ovarian follicle development [IGI, NAS]
- palate development [IGI]
- positive regulation of cellular protein metabolic process [IDA]
- positive regulation of erythrocyte differentiation [IDA]
- positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [IDA]
- positive regulation of follicle-stimulating hormone secretion [TAS]
- positive regulation of ovulation [ISS]
- positive regulation of pathway-restricted SMAD protein phosphorylation [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription, DNA-templated [IDA]
- progesterone secretion [IGI]
- regulation of MAPK cascade [IBA]
- regulation of follicle-stimulating hormone secretion [IGI]
- regulation of transcription from RNA polymerase II promoter [IDA]
- response to drug [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ALDH4A1
ALDH4, P5CD, P5CDh, RP11-128M10.1
aldehyde dehydrogenase 4 family, member A1
GO Process (5)
GO Function (4)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.
Mitochondrial protein (MP) assemblies undergo alterations during neurogenesis, a complex process vital in brain homeostasis and disease. Yet which MP assemblies remodel during differentiation remains unclear. Here, using mass spectrometry-based co-fractionation profiles and phosphoproteomics, we generated mitochondrial interaction maps of human pluripotent embryonal carcinoma stem cells and differentiated neuronal-like cells, which presented as two discrete cell populations by single-cell RNA ... [more]
iScience Sep. 27, 2019; 19();1114-1132 [Pubmed: 31536960]
Quantitative Score
- 1.675968596 [Confidence Score]
Throughput
- High Throughput
Additional Notes
- Protein pairs with Sigma LLS score >= 1.45 derived from Ntera2 embryonic carcinoma stem cells (ECSC)
Curated By
- BioGRID