BAIT
LGALS3
CBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2
lectin, galactoside-binding, soluble, 3
GO Process (18)
GO Function (5)
GO Component (9)
Gene Ontology Biological Process
- eosinophil chemotaxis [IDA]
- epithelial cell differentiation [IEP]
- innate immune response [TAS]
- macrophage chemotaxis [IDA]
- monocyte chemotaxis [IDA]
- mononuclear cell migration [IDA]
- negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [ISS]
- negative regulation of T cell receptor signaling pathway [ISS]
- negative regulation of endocytosis [IDA]
- negative regulation of extrinsic apoptotic signaling pathway [IDA]
- negative regulation of immunological synapse formation [ISS]
- neutrophil chemotaxis [IDA]
- positive chemotaxis [IDA]
- positive regulation of calcium ion import [IDA]
- positive regulation of mononuclear cell migration [IDA]
- regulation of T cell apoptotic process [IDA]
- regulation of T cell proliferation [IMP]
- regulation of extrinsic apoptotic signaling pathway via death domain receptors [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
AK3
AK3L1, AK6, AKL3L, AKL3L1, FIX, RP11-6J24.4
adenylate kinase 3
GO Process (5)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.
Mitochondrial protein (MP) assemblies undergo alterations during neurogenesis, a complex process vital in brain homeostasis and disease. Yet which MP assemblies remodel during differentiation remains unclear. Here, using mass spectrometry-based co-fractionation profiles and phosphoproteomics, we generated mitochondrial interaction maps of human pluripotent embryonal carcinoma stem cells and differentiated neuronal-like cells, which presented as two discrete cell populations by single-cell RNA ... [more]
iScience Sep. 27, 2019; 19();1114-1132 [Pubmed: 31536960]
Quantitative Score
- 1.550263661 [Confidence Score]
Throughput
- High Throughput
Additional Notes
- Protein pairs with Sigma LLS score >= 1.45 derived from Ntera2 embryonic carcinoma stem cells (ECSC)
Curated By
- BioGRID