BAIT
SOD1
ALS, ALS1, HEL-S-44, IPOA, SOD, hSod1, homodimer
superoxide dismutase 1, soluble
GO Process (50)
GO Function (9)
GO Component (17)
Gene Ontology Biological Process
- activation of MAPK activity [ISS]
- anterograde axon cargo transport [ISS]
- auditory receptor cell stereocilium organization [ISS]
- blood coagulation [TAS]
- cell aging [IMP]
- cellular iron ion homeostasis [ISS]
- embryo implantation [ISS, NAS]
- glutathione metabolic process [ISS]
- heart contraction [IDA]
- hydrogen peroxide biosynthetic process [IDA, ISS]
- locomotory behavior [ISS]
- muscle cell cellular homeostasis [ISS]
- myeloid cell homeostasis [ISS]
- negative regulation of cholesterol biosynthetic process [IDA]
- negative regulation of neuron apoptotic process [ISS]
- neurofilament cytoskeleton organization [ISS]
- ovarian follicle development [ISS]
- peripheral nervous system myelin maintenance [ISS]
- placenta development [NAS]
- platelet activation [TAS]
- platelet degranulation [TAS]
- positive regulation of apoptotic process [IC]
- positive regulation of catalytic activity [IDA]
- positive regulation of cytokine production [IDA]
- positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [IMP]
- positive regulation of superoxide anion generation [IDA]
- reactive oxygen species metabolic process [IDA]
- regulation of Rac GTPase activity [IDA]
- regulation of T cell differentiation in thymus [NAS]
- regulation of blood pressure [ISS]
- regulation of mitochondrial membrane potential [IMP]
- regulation of multicellular organism growth [ISS]
- regulation of organ growth [NAS]
- regulation of protein kinase activity [IDA]
- relaxation of vascular smooth muscle [ISS]
- removal of superoxide radicals [IBA, IC, ISS]
- response to axon injury [ISS]
- response to drug [ISS]
- response to ethanol [ISS]
- response to heat [ISS]
- response to hydrogen peroxide [ISS]
- response to organic substance [IDA]
- response to superoxide [IDA]
- retina homeostasis [ISS]
- retrograde axon cargo transport [ISS]
- sensory perception of sound [ISS]
- spermatogenesis [ISS]
- superoxide metabolic process [IDA, ISS]
- thymus development [NAS]
- transmission of nerve impulse [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cytoplasm [IDA]
- cytoplasmic vesicle [IDA]
- cytosol [IDA, TAS]
- dendrite cytoplasm [IDA]
- extracellular matrix [IDA]
- extracellular region [TAS]
- extracellular space [IDA]
- extracellular vesicular exosome [IDA]
- mitochondrial intermembrane space [TAS]
- mitochondrial matrix [NAS]
- mitochondrion [IDA]
- neuronal cell body [IDA]
- nucleoplasm [IDA]
- nucleus [IDA]
- peroxisome [IDA, ISS]
- plasma membrane [IDA]
- protein complex [IDA]
Homo sapiens
PREY
GSTO1
GSTO 1-1, GSTTLp28, HEL-S-21, P28, SPG-R, RP11-99N20.1
glutathione S-transferase omega 1
GO Process (11)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- L-ascorbic acid metabolic process [IDA]
- cellular response to arsenic-containing substance [IDA]
- glutathione derivative biosynthetic process [TAS]
- negative regulation of ryanodine-sensitive calcium-release channel activity [IDA]
- positive regulation of ryanodine-sensitive calcium-release channel activity [IDA]
- positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [IC]
- regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [IC]
- regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [IDA]
- small molecule metabolic process [TAS]
- xenobiotic catabolic process [IDA]
- xenobiotic metabolic process [TAS]
Gene Ontology Molecular Function
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.
Mitochondrial protein (MP) assemblies undergo alterations during neurogenesis, a complex process vital in brain homeostasis and disease. Yet which MP assemblies remodel during differentiation remains unclear. Here, using mass spectrometry-based co-fractionation profiles and phosphoproteomics, we generated mitochondrial interaction maps of human pluripotent embryonal carcinoma stem cells and differentiated neuronal-like cells, which presented as two discrete cell populations by single-cell RNA ... [more]
iScience Sep. 27, 2019; 19();1114-1132 [Pubmed: 31536960]
Quantitative Score
- 1.539921605 [Confidence Score]
Throughput
- High Throughput
Additional Notes
- Protein pairs with Sigma LLS score >= 1.45 derived from Ntera2 embryonic carcinoma stem cells (ECSC)
Curated By
- BioGRID