BAIT
PRDX5
ACR1, AOEB166, B166, HEL-S-55, PLP, PMP20, PRDX6, PRXV, prx-V, SBBI10
peroxiredoxin 5
GO Process (12)
GO Function (8)
GO Component (12)
Gene Ontology Biological Process
- NADPH oxidation [IDA]
- cellular response to reactive oxygen species [IMP]
- hydrogen peroxide catabolic process [IDA]
- inflammatory response [TAS]
- negative regulation of apoptotic process [IMP]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [IMP]
- negative regulation of oxidoreductase activity [IDA]
- negative regulation of transcription from RNA polymerase III promoter [IDA]
- positive regulation of collagen biosynthetic process [IDA]
- reactive nitrogen species metabolic process [IDA]
- regulation of apoptosis involved in tissue homeostasis [IDA]
- response to oxidative stress [IDA]
Gene Ontology Molecular Function- RNA polymerase III regulatory region DNA binding [IDA]
- antioxidant activity [IDA]
- cysteine-type endopeptidase inhibitor activity involved in apoptotic process [IMP]
- peroxidase activity [IDA]
- peroxiredoxin activity [IDA]
- peroxynitrite reductase activity [IDA]
- protein dimerization activity [IDA]
- receptor binding [IPI]
- RNA polymerase III regulatory region DNA binding [IDA]
- antioxidant activity [IDA]
- cysteine-type endopeptidase inhibitor activity involved in apoptotic process [IMP]
- peroxidase activity [IDA]
- peroxiredoxin activity [IDA]
- peroxynitrite reductase activity [IDA]
- protein dimerization activity [IDA]
- receptor binding [IPI]
Gene Ontology Cellular Component
- cytoplasm [IDA]
- cytoplasmic vesicle [IDA]
- cytosol [IDA, TAS]
- extracellular space [IDA]
- extracellular vesicular exosome [IDA]
- intracellular membrane-bounded organelle [IDA]
- mitochondrial matrix [TAS]
- mitochondrion [IDA]
- nucleus [IDA]
- perinuclear region of cytoplasm [IDA]
- peroxisomal matrix [IDA]
- peroxisome [IDA]
Homo sapiens
PREY
RAB11A
YL8
RAB11A, member RAS oncogene family
GO Process (24)
GO Function (7)
GO Component (12)
Gene Ontology Biological Process
- GTP catabolic process [IBA, IDA]
- Rab protein signal transduction [IBA]
- astral microtubule organization [IMP]
- cytokinesis [IMP]
- establishment of protein localization to membrane [IMP]
- establishment of protein localization to organelle [IMP]
- establishment of vesicle localization [IMP]
- exocytosis [IBA]
- exosomal secretion [IMP]
- intracellular protein transport [IBA]
- melanosome transport [IBA, ISS]
- mitotic metaphase plate congression [IMP]
- multivesicular body assembly [IMP]
- neuron projection development [IMP]
- plasma membrane to endosome transport [NAS]
- positive regulation of G2/M transition of mitotic cell cycle [IMP]
- positive regulation of epithelial cell migration [IMP]
- protein localization to plasma membrane [IDA]
- regulation of multivesicular body size [IMP]
- regulation of vesicle-mediated transport [IMP]
- spindle assembly involved in mitosis [IMP]
- transmembrane transport [TAS]
- vesicle-mediated transport [IDA]
- water transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cleavage furrow [IDA]
- cytoplasmic vesicle [IDA]
- cytoplasmic vesicle membrane [TAS]
- extracellular vesicular exosome [IDA]
- kinetochore microtubule [IDA]
- multivesicular body [IDA]
- phagocytic vesicle [IDA]
- protein complex [IDA]
- recycling endosome [IBA, IDA, ISS]
- spindle pole [IDA]
- trans-Golgi network [IDA]
- vesicle [IDA]
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.
Mitochondrial protein (MP) assemblies undergo alterations during neurogenesis, a complex process vital in brain homeostasis and disease. Yet which MP assemblies remodel during differentiation remains unclear. Here, using mass spectrometry-based co-fractionation profiles and phosphoproteomics, we generated mitochondrial interaction maps of human pluripotent embryonal carcinoma stem cells and differentiated neuronal-like cells, which presented as two discrete cell populations by single-cell RNA ... [more]
iScience Sep. 27, 2019; 19();1114-1132 [Pubmed: 31536960]
Quantitative Score
- 1.460943324 [Confidence Score]
Throughput
- High Throughput
Additional Notes
- Protein pairs with Sigma LLS score >= 1.45 derived from Ntera2 embryonic carcinoma stem cells (ECSC)
Curated By
- BioGRID