BAIT
PRDX2
HEL-S-2a, NKEF-B, NKEFB, PRP, PRX2, PRXII, PTX1, TDPX1, TPX1, TSA
peroxiredoxin 2
GO Process (6)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
CLIC4
CLIC4L, H1, MTCLIC, huH1, p64H1
chloride intracellular channel 4
GO Process (8)
GO Function (2)
GO Component (16)
Gene Ontology Biological Process
- cell differentiation [TAS]
- cellular response to calcium ion [IMP]
- chloride transmembrane transport [TAS]
- chloride transport [NAS]
- establishment or maintenance of apical/basal cell polarity [NAS]
- keratinocyte differentiation [IMP]
- negative regulation of cell migration [IDA]
- regulation of cytoskeleton organization [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- actin cytoskeleton [TAS]
- apical part of cell [IDA]
- cell surface [IDA]
- cell-cell junction [IDA]
- centrosome [IDA]
- cytoplasm [IDA]
- cytosol [IDA]
- extracellular vesicular exosome [IDA]
- intracellular [IDA]
- microtubule cytoskeleton [IDA]
- microvillus [IDA]
- midbody [IDA]
- mitochondrion [IDA]
- nuclear matrix [IDA]
- perinuclear region of cytoplasm [IDA]
- plasma membrane [IDA]
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.
Mitochondrial protein (MP) assemblies undergo alterations during neurogenesis, a complex process vital in brain homeostasis and disease. Yet which MP assemblies remodel during differentiation remains unclear. Here, using mass spectrometry-based co-fractionation profiles and phosphoproteomics, we generated mitochondrial interaction maps of human pluripotent embryonal carcinoma stem cells and differentiated neuronal-like cells, which presented as two discrete cell populations by single-cell RNA ... [more]
iScience Sep. 27, 2019; 19();1114-1132 [Pubmed: 31536960]
Quantitative Score
- 1.455678993 [Confidence Score]
Throughput
- High Throughput
Additional Notes
- Protein pairs with Sigma LLS score >= 1.45 derived from Ntera2 embryonic carcinoma stem cells (ECSC)
Curated By
- BioGRID