BAIT
ANXA6
ANX6, CBP68
annexin A6
GO Process (2)
GO Function (8)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
TAOK3
DPK, JIK, MAP3K18
TAO kinase 3
GO Process (11)
GO Function (5)
GO Component (1)
Gene Ontology Biological Process
- MAPK cascade [IMP]
- activation of MAPKK activity [IBA]
- cellular response to DNA damage stimulus [IDA]
- mitotic G2 DNA damage checkpoint [IMP]
- negative regulation of JNK cascade [IDA]
- negative regulation of protein kinase activity [TAS]
- positive regulation of JNK cascade [IMP]
- positive regulation of JUN kinase activity [IMP]
- positive regulation of stress-activated MAPK cascade [IMP]
- protein autophosphorylation [IDA]
- protein phosphorylation [IDA, IMP]
Gene Ontology Molecular Function
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.
Mitochondrial protein (MP) assemblies undergo alterations during neurogenesis, a complex process vital in brain homeostasis and disease. Yet which MP assemblies remodel during differentiation remains unclear. Here, using mass spectrometry-based co-fractionation profiles and phosphoproteomics, we generated mitochondrial interaction maps of human pluripotent embryonal carcinoma stem cells and differentiated neuronal-like cells, which presented as two discrete cell populations by single-cell RNA ... [more]
iScience Sep. 27, 2019; 19();1114-1132 [Pubmed: 31536960]
Quantitative Score
- 1.622815606 [Confidence Score]
Throughput
- High Throughput
Additional Notes
- Protein pairs with Sigma LLS score >= 1.45 derived from NTera2 retinoic acid (RA)-induced differentiated neuronal-like cells (DNLCs)
Curated By
- BioGRID