BAIT
LAP3
HEL-S-106, LAP, LAPEP, PEPS
leucine aminopeptidase 3
GO Process (1)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ACOX1
ACOX, PALMCOX, SCOX
acyl-CoA oxidase 1, palmitoyl
GO Process (13)
GO Function (6)
GO Component (8)
Gene Ontology Biological Process
- alpha-linolenic acid metabolic process [TAS]
- cellular lipid metabolic process [TAS]
- fatty acid beta-oxidation using acyl-CoA oxidase [IMP, TAS]
- fatty acid oxidation [IGI, IMP]
- generation of precursor metabolites and energy [IMP]
- lipid homeostasis [IDA, IGI]
- lipid metabolic process [IDA]
- peroxisome fission [IGI]
- positive regulation of cholesterol homeostasis [IGI]
- prostaglandin metabolic process [IMP]
- small molecule metabolic process [TAS]
- unsaturated fatty acid metabolic process [TAS]
- very long-chain fatty acid metabolic process [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.
Mitochondrial protein (MP) assemblies undergo alterations during neurogenesis, a complex process vital in brain homeostasis and disease. Yet which MP assemblies remodel during differentiation remains unclear. Here, using mass spectrometry-based co-fractionation profiles and phosphoproteomics, we generated mitochondrial interaction maps of human pluripotent embryonal carcinoma stem cells and differentiated neuronal-like cells, which presented as two discrete cell populations by single-cell RNA ... [more]
iScience Sep. 27, 2019; 19();1114-1132 [Pubmed: 31536960]
Quantitative Score
- 1.51991263 [Confidence Score]
Throughput
- High Throughput
Additional Notes
- Protein pairs with Sigma LLS score >= 1.45 derived from NTera2 retinoic acid (RA)-induced differentiated neuronal-like cells (DNLCs)
Curated By
- BioGRID