ATF2
Gene Ontology Biological Process
- MyD88-dependent toll-like receptor signaling pathway [TAS]
- MyD88-independent toll-like receptor signaling pathway [TAS]
- TRIF-dependent toll-like receptor signaling pathway [TAS]
- cellular response to DNA damage stimulus [IDA, IMP]
- chromatin organization [TAS]
- histone acetylation [IDA]
- innate immune response [TAS]
- intra-S DNA damage checkpoint [IMP]
- positive regulation of mitochondrial membrane permeability involved in apoptotic process [IMP]
- positive regulation of sequence-specific DNA binding transcription factor activity [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- regulation of sequence-specific DNA binding transcription factor activity [TAS]
- regulation of transcription from RNA polymerase II promoter [IC]
- regulation of transcription, DNA-templated [IMP]
- response to osmotic stress [IDA]
- stress-activated MAPK cascade [TAS]
- toll-like receptor 10 signaling pathway [TAS]
- toll-like receptor 2 signaling pathway [TAS]
- toll-like receptor 3 signaling pathway [TAS]
- toll-like receptor 4 signaling pathway [TAS]
- toll-like receptor 5 signaling pathway [TAS]
- toll-like receptor 9 signaling pathway [TAS]
- toll-like receptor TLR1:TLR2 signaling pathway [TAS]
- toll-like receptor TLR6:TLR2 signaling pathway [TAS]
- toll-like receptor signaling pathway [TAS]
- transcription from RNA polymerase II promoter [IC]
Gene Ontology Molecular Function- RNA polymerase II activating transcription factor binding [IPI]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IC]
- RNA polymerase II regulatory region sequence-specific DNA binding [IMP]
- RNA polymerase II transcription factor binding transcription factor activity [IC]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IC]
- cAMP response element binding [IDA]
- cAMP response element binding protein binding [IDA]
- enhancer sequence-specific DNA binding [IDA]
- histone acetyltransferase activity [IDA]
- protein binding [IPI]
- protein kinase binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription coactivator activity [TAS]
- RNA polymerase II activating transcription factor binding [IPI]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IC]
- RNA polymerase II regulatory region sequence-specific DNA binding [IMP]
- RNA polymerase II transcription factor binding transcription factor activity [IC]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IC]
- cAMP response element binding [IDA]
- cAMP response element binding protein binding [IDA]
- enhancer sequence-specific DNA binding [IDA]
- histone acetyltransferase activity [IDA]
- protein binding [IPI]
- protein kinase binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription coactivator activity [TAS]
Gene Ontology Cellular Component
CSNK2A1
Gene Ontology Biological Process
- axon guidance [TAS]
- chaperone-mediated protein folding [TAS]
- mitotic cell cycle [TAS]
- mitotic spindle checkpoint [IMP]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [IMP]
- positive regulation of Wnt signaling pathway [IMP]
- positive regulation of cell growth [IDA]
- positive regulation of cell proliferation [IDA]
- positive regulation of protein catabolic process [IDA]
- protein phosphorylation [IDA]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Reconstituted Complex
An interaction is inferred between proteins in vitro. This can include proteins in recombinant form or proteins isolated directly from cells with recombinant or purified bait. For example, GST pull-down assays where a GST-tagged protein is first isolated and then used to fish interactors from cell lysates are considered reconstituted complexes (e.g. PUBMED: 14657240, Fig. 4A or PUBMED: 14761940, Fig. 5). This can also include gel-shifts, surface plasmon resonance, isothermal titration calorimetry (ITC) and bio-layer interferometry (BLI) experiments. The bait-hit directionality may not be clear for 2 interacting proteins. In these cases the directionality is up to the discretion of the curator.
Publication
Casein kinase II interacts with the bZIP domains of several transcription factors.
Casein kinase II (CKII) is thought to regulate a broad range of transcription factors, but its mode of action is not well characterized. We previously showed that CKII is co-purified with the ATF family of transcription factors using DNA-affinity latex beads. Here we report a functional and physical interaction between CKII and transcription factors. We demonstrate that CKII binds through ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ATF2 CSNK2A1 | Far Western Far Western An interaction is detected between a protein immobilized on a membrane and a purified protein probe. | Low | - | BioGRID | - |
Curated By
- BioGRID