BAIT
DNM1
Dnm
dynamin 1
GO Process (11)
GO Function (8)
GO Component (11)
Gene Ontology Biological Process
- G-protein coupled receptor internalization [IMP]
- adult locomotory behavior [ISO]
- endocytosis [ISO]
- endosome organization [ISO]
- positive regulation of synaptic vesicle recycling [IMP]
- protein tetramerization [ISO]
- receptor internalization [IMP]
- receptor-mediated endocytosis [IMP, ISO]
- sensory perception of sound [ISO]
- synaptic transmission, GABAergic [ISO]
- toxin transport [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
CLIC4
CLIC4L, H1, MTCLIC, huH1, p64H1
chloride intracellular channel 4
GO Process (8)
GO Function (2)
GO Component (16)
Gene Ontology Biological Process
- cell differentiation [TAS]
- cellular response to calcium ion [IMP]
- chloride transmembrane transport [TAS]
- chloride transport [NAS]
- establishment or maintenance of apical/basal cell polarity [NAS]
- keratinocyte differentiation [IMP]
- negative regulation of cell migration [IDA]
- regulation of cytoskeleton organization [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- actin cytoskeleton [TAS]
- apical part of cell [IDA]
- cell surface [IDA]
- cell-cell junction [IDA]
- centrosome [IDA]
- cytoplasm [IDA]
- cytosol [IDA]
- extracellular vesicular exosome [IDA]
- intracellular [IDA]
- microtubule cytoskeleton [IDA]
- microvillus [IDA]
- midbody [IDA]
- mitochondrion [IDA]
- nuclear matrix [IDA]
- perinuclear region of cytoplasm [IDA]
- plasma membrane [IDA]
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Chloride intracellular channel protein CLIC4 (p64H1) binds directly to brain dynamin I in a complex containing actin, tubulin and 14-3-3 isoforms.
Mammalian chloride intracellular channel (CLIC) (p64-related) proteins are widely expressed, with an unusual dual localization as both soluble and integral membrane proteins. The molecular basis for their cellular localization and ion channel activity remains unclear. To help in addressing these problems, we identified novel rat brain CLIC4 (p64H1) binding partners by affinity chromatography, mass spectrometric analysis and microsequencing. Brain CLIC4 ... [more]
Biochem. J. Oct. 01, 2001; 359(0);55-64 [Pubmed: 11563969]
Throughput
- Low Throughput
Curated By
- BioGRID