BAIT
CPNE2
COPN2, CPN2
copine II
GO Process (0)
GO Function (0)
GO Component (1)
Gene Ontology Cellular Component
Homo sapiens
PREY
RDX
AA516625
radixin
GO Process (5)
GO Function (3)
GO Component (17)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- T-tubule [ISO]
- apical part of cell [IDA]
- cell periphery [ISO]
- cell tip [ISO]
- cell-cell adherens junction [ISO]
- cleavage furrow [ISO]
- extracellular space [ISO]
- extracellular vesicular exosome [ISO]
- filopodium [IDA]
- focal adhesion [ISO]
- lamellipodium [IDA]
- microvillus [IDA, ISO]
- midbody [ISO]
- myelin sheath [IDA]
- plasma membrane [ISO]
- ruffle [IDA]
- stereocilium [IDA]
Mus musculus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif.
We provide evidence that copines, members of a ubiquitous family of calcium-dependent, membrane-binding proteins, may represent a universal transduction pathway for calcium signaling because we find copines are capable of interacting with a wide variety of "target" proteins including MEK1, protein phosphatase 5, and the CDC42-regulated kinase, that are themselves components of intracellular signaling pathways. The copine target proteins were ... [more]
J. Biol. Chem. Mar. 21, 2003; 278(12);10048-54 [Pubmed: 12522145]
Throughput
- Low Throughput
Curated By
- BioGRID