BAIT
CPNE2
COPN2, CPN2
copine II
GO Process (0)
GO Function (0)
GO Component (1)
Gene Ontology Cellular Component
Homo sapiens
PREY
MYCBP2
AU023734, AW107953, AW546647, C130061D10Rik, Pam, Phr1, R75243
MYC binding protein 2
GO Process (7)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- branchiomotor neuron axon guidance [IMP]
- cell morphogenesis involved in neuron differentiation [IMP]
- central nervous system projection neuron axonogenesis [IMP]
- motor neuron axon guidance [IMP]
- negative regulation of protein catabolic process [IDA]
- regulation of cytoskeleton organization [IMP]
- regulation of protein localization [IMP]
Gene Ontology Molecular Function
Mus musculus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif.
We provide evidence that copines, members of a ubiquitous family of calcium-dependent, membrane-binding proteins, may represent a universal transduction pathway for calcium signaling because we find copines are capable of interacting with a wide variety of "target" proteins including MEK1, protein phosphatase 5, and the CDC42-regulated kinase, that are themselves components of intracellular signaling pathways. The copine target proteins were ... [more]
J. Biol. Chem. Mar. 21, 2003; 278(12);10048-54 [Pubmed: 12522145]
Throughput
- Low Throughput
Curated By
- BioGRID