BAIT
GIPC1
C19orf3, GIPC, GLUT1CBP, Hs.6454, IIP-1, NIP, RGS19IP1, SEMCAP, SYNECTIIN, SYNECTIN, TIP-2
GIPC PDZ domain containing family, member 1
GO Process (10)
GO Function (5)
GO Component (10)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [NAS]
- endothelial cell migration [ISS]
- glutamate secretion [ISS]
- negative regulation of proteasomal ubiquitin-dependent protein catabolic process [ISS]
- positive regulation of cytokinesis [IMP]
- positive regulation of transforming growth factor beta receptor signaling pathway [ISS]
- protein targeting [ISS]
- regulation of protein stability [ISS]
- regulation of synaptic plasticity [ISS]
- synaptic transmission [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
RAB11FIP5
GAF1, RIP11, pp75
RAB11 family interacting protein 5 (class I)
GO Process (4)
GO Function (3)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.
Mitochondrial protein (MP) assemblies undergo alterations during neurogenesis, a complex process vital in brain homeostasis and disease. Yet which MP assemblies remodel during differentiation remains unclear. Here, using mass spectrometry-based co-fractionation profiles and phosphoproteomics, we generated mitochondrial interaction maps of human pluripotent embryonal carcinoma stem cells and differentiated neuronal-like cells, which presented as two discrete cell populations by single-cell RNA ... [more]
iScience Sep. 27, 2019; 19();1114-1132 [Pubmed: 31536960]
Quantitative Score
- 1.655942776 [Confidence Score]
Throughput
- High Throughput
Additional Notes
- Protein pairs with Sigma LLS score >= 1.45 derived from NTera2 retinoic acid (RA)-induced differentiated neuronal-like cells (DNLCs)
Curated By
- BioGRID