BAIT
PHF8
JHDM1F, MRXSSD, ZNF422, RP13-444K19.2
PHD finger protein 8
GO Process (10)
GO Function (11)
GO Component (4)
Gene Ontology Biological Process
- G1/S transition of mitotic cell cycle [IMP]
- brain development [ISS]
- histone H3-K27 demethylation [IDA]
- histone H3-K36 demethylation [IDA]
- histone H3-K9 demethylation [IDA]
- histone H4-K20 demethylation [IDA]
- mitotic cell cycle [TAS]
- negative regulation of chromatin silencing at rDNA [IDA]
- positive regulation of transcription from RNA polymerase I promoter [IDA]
- positive regulation of transcription, DNA-templated [IDA, IMP]
Gene Ontology Molecular Function- chromatin binding [IDA]
- histone demethylase activity [IDA]
- histone demethylase activity (H3-K27 specific) [IDA]
- histone demethylase activity (H3-K36 specific) [IDA]
- histone demethylase activity (H3-K9 specific) [IDA]
- histone demethylase activity (H4-K20 specific) [IDA]
- iron ion binding [IDA]
- methylated histone binding [IDA]
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [IDA]
- protein binding [IPI]
- zinc ion binding [IDA]
- chromatin binding [IDA]
- histone demethylase activity [IDA]
- histone demethylase activity (H3-K27 specific) [IDA]
- histone demethylase activity (H3-K36 specific) [IDA]
- histone demethylase activity (H3-K9 specific) [IDA]
- histone demethylase activity (H4-K20 specific) [IDA]
- iron ion binding [IDA]
- methylated histone binding [IDA]
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [IDA]
- protein binding [IPI]
- zinc ion binding [IDA]
Gene Ontology Cellular Component
Homo sapiens
PREY
VDAC3
HD-VDAC3, VDAC-3
voltage-dependent anion channel 3
GO Process (1)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.
Mitochondrial protein (MP) assemblies undergo alterations during neurogenesis, a complex process vital in brain homeostasis and disease. Yet which MP assemblies remodel during differentiation remains unclear. Here, using mass spectrometry-based co-fractionation profiles and phosphoproteomics, we generated mitochondrial interaction maps of human pluripotent embryonal carcinoma stem cells and differentiated neuronal-like cells, which presented as two discrete cell populations by single-cell RNA ... [more]
iScience Sep. 27, 2019; 19();1114-1132 [Pubmed: 31536960]
Quantitative Score
- 1.46022282 [Confidence Score]
Throughput
- High Throughput
Additional Notes
- Protein pairs with Sigma LLS score >= 1.45 derived from NTera2 retinoic acid (RA)-induced differentiated neuronal-like cells (DNLCs)
Curated By
- BioGRID