PREY

CPNE1

COPN1, CPN1, RP1-309K20.2
copine I
GO Process (2)
GO Function (3)
GO Component (1)
Homo sapiens

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif.

Tomsig JL, Snyder SL, Creutz CE

We provide evidence that copines, members of a ubiquitous family of calcium-dependent, membrane-binding proteins, may represent a universal transduction pathway for calcium signaling because we find copines are capable of interacting with a wide variety of "target" proteins including MEK1, protein phosphatase 5, and the CDC42-regulated kinase, that are themselves components of intracellular signaling pathways. The copine target proteins were ... [more]

J. Biol. Chem. Mar. 21, 2003; 278(12);10048-54 [Pubmed: 12522145]

Throughput

  • Low Throughput

Curated By

  • BioGRID