BAIT
SQSTM1
Osi, ZIP, ZIP3
sequestosome 1
GO Process (7)
GO Function (8)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
PRKCD
Pkcd
protein kinase C, delta
GO Process (48)
GO Function (9)
GO Component (10)
Gene Ontology Biological Process
- B cell proliferation [ISO]
- aging [IEP]
- apoptotic process [ISO]
- aspartate transport [IMP]
- cellular response to glucose starvation [IEP]
- cellular response to insulin stimulus [IEP]
- cellular senescence [ISO]
- collagen metabolic process [IMP]
- defense response to bacterium [ISO, ISS]
- immunoglobulin mediated immune response [ISO]
- interleukin-10 production [ISO]
- interleukin-12 production [ISO]
- intracellular signal transduction [IDA]
- negative regulation of MAP kinase activity [ISO]
- negative regulation of actin filament polymerization [ISO, ISS]
- negative regulation of filopodium assembly [ISO, ISS]
- negative regulation of glial cell apoptotic process [ISO, ISS]
- negative regulation of insulin receptor signaling pathway [ISO]
- negative regulation of peptidyl-tyrosine phosphorylation [ISO]
- negative regulation of platelet aggregation [ISO, ISS]
- neutrophil activation [ISO]
- peptidyl-threonine phosphorylation [ISO]
- positive regulation of MAP kinase activity [IMP]
- positive regulation of MAPK cascade [IMP]
- positive regulation of apoptotic process [IMP]
- positive regulation of apoptotic signaling pathway [ISO]
- positive regulation of ceramide biosynthetic process [ISO]
- positive regulation of glucose import [IMP]
- positive regulation of glucosylceramide catabolic process [ISO]
- positive regulation of phospholipid scramblase activity [ISO]
- positive regulation of protein dephosphorylation [ISO]
- positive regulation of response to DNA damage stimulus [ISO]
- positive regulation of sphingomyelin catabolic process [ISO]
- positive regulation of superoxide anion generation [ISO, ISS]
- protein autophosphorylation [IDA]
- protein phosphorylation [IDA, ISO]
- response to amino acid [IEP]
- response to drug [IEP]
- response to ethanol [IEP]
- response to glucose [IEP]
- response to heat [IEP]
- response to hydrogen peroxide [IEP]
- response to hypoxia [IEP]
- response to mechanical stimulus [IEP]
- response to organic cyclic compound [IEP]
- response to organonitrogen compound [IEP]
- response to oxidative stress [IMP]
- termination of signal transduction [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Protein Kinase C (PKC)? Pseudosubstrate Inhibitor Peptide Promiscuously Binds PKC Family Isoforms and Disrupts Conventional PKC Targeting and Translocation.
PKM? is generated via an alternative transcriptional start site in the atypical protein kinase C (PKC)? isoform, which removes N-terminal regulatory elements, including the inhibitory pseudosubstrate domain, consequently rendering the kinase constitutively active. Persistent PKM? activity has been proposed as a molecular mechanism for the long-term maintenance of synaptic plasticity underlying some forms of memory. Many studies supporting a role ... [more]
Mol. Pharmacol. Oct. 01, 2015; 88(4);728-35 [Pubmed: 26199377]
Throughput
- Low Throughput
Curated By
- BioGRID