BAIT
TIA1
2310050N03Rik, AI256674, TIA-1, mTIA-1
cytotoxic granule-associated RNA binding protein 1
GO Process (3)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PFKM
AI131669, ATP-PFK, PFK-A, PFK-M, Pfk-4, Pfk4, Pfka, Pfkx
phosphofructokinase, muscle
GO Process (10)
GO Function (12)
GO Component (5)
Gene Ontology Biological Process
- carbohydrate phosphorylation [IMP, ISO]
- fructose 1,6-bisphosphate metabolic process [ISO]
- fructose 6-phosphate metabolic process [ISO]
- glucose homeostasis [IMP]
- glycolytic process [IDA, IMP, ISO, ISS]
- glycolytic process through fructose-6-phosphate [IC]
- muscle cell cellular homeostasis [ISO]
- positive regulation of insulin secretion [IMP]
- protein homotetramerization [ISO]
- protein oligomerization [ISO]
Gene Ontology Molecular Function- 6-phosphofructokinase activity [IDA, IMP, ISO, ISS]
- AMP binding [ISO]
- ATP binding [ISO]
- carbohydrate binding [ISO]
- fructose binding [ISO]
- fructose-6-phosphate binding [ISO]
- identical protein binding [ISO]
- kinase binding [ISO]
- phosphofructokinase activity [IDA, ISO]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein homodimerization activity [IDA]
- 6-phosphofructokinase activity [IDA, IMP, ISO, ISS]
- AMP binding [ISO]
- ATP binding [ISO]
- carbohydrate binding [ISO]
- fructose binding [ISO]
- fructose-6-phosphate binding [ISO]
- identical protein binding [ISO]
- kinase binding [ISO]
- phosphofructokinase activity [IDA, ISO]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein homodimerization activity [IDA]
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity.
Dendritic mislocalization of microtubule associated protein tau is a hallmark of tauopathies, but the role of dendritic tau is unknown. We now report that tau interacts with the RNA-binding protein (RBP) TIA1 in brain tissue, and we present the brain-protein interactome network for TIA1. Analysis of the TIA1 interactome in brain tissue from wild-type (WT) and tau knockout mice demonstrates ... [more]
Cell Rep Dec. 17, 2015; 15(7);1455-1466 [Pubmed: 27160897]
Throughput
- High Throughput
Curated By
- BioGRID