BAIT
TIA1
2310050N03Rik, AI256674, TIA-1, mTIA-1
cytotoxic granule-associated RNA binding protein 1
GO Process (3)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
RAB14
0610030G24Rik, 2810475J17Rik, A830021G03Rik, AI314285, AI649155, D030017L14Rik, RP23-186B18.6
RAB14, member RAS oncogene family
GO Process (11)
GO Function (6)
GO Component (22)
Gene Ontology Biological Process
- GTP catabolic process [IBA, ISO]
- Golgi to endosome transport [IMP]
- Rab protein signal transduction [IBA]
- apical protein localization [ISO]
- body fluid secretion [ISO]
- embryo development [IMP]
- endocytic recycling [ISO]
- fibroblast growth factor receptor signaling pathway [IMP]
- intracellular protein transport [IBA]
- phagolysosome assembly involved in apoptotic cell clearance [IBA]
- regulation of protein localization [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [IBA]
- Golgi stack [ISO]
- alveolar lamellar body [ISO]
- apical plasma membrane [ISO]
- cell [IMP]
- cytoplasm [IMP]
- cytosol [ISO]
- early endosome [IBA, ISO]
- extracellular vesicular exosome [ISO]
- intracellular [IMP, ISO]
- intracellular membrane-bounded organelle [ISO]
- late endosome [ISO]
- lysosomal membrane [ISO]
- lysosome [ISO]
- nuclear outer membrane-endoplasmic reticulum membrane network [ISO]
- perinuclear region of cytoplasm [ISO]
- phagocytic vesicle [IBA, ISO]
- plasma membrane [ISO]
- recycling endosome [ISO]
- rough endoplasmic reticulum [ISO]
- trans-Golgi network transport vesicle [ISO]
- transport vesicle [ISO]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity.
Dendritic mislocalization of microtubule associated protein tau is a hallmark of tauopathies, but the role of dendritic tau is unknown. We now report that tau interacts with the RNA-binding protein (RBP) TIA1 in brain tissue, and we present the brain-protein interactome network for TIA1. Analysis of the TIA1 interactome in brain tissue from wild-type (WT) and tau knockout mice demonstrates ... [more]
Cell Rep Dec. 17, 2015; 15(7);1455-1466 [Pubmed: 27160897]
Throughput
- High Throughput
Curated By
- BioGRID